All AMS members and other interested parties are warmly invited to join the symposium on Muscle Structure and Function hosted by dr. Rob Wust.

Muscle physiologist Dr. Brian Glancy* (NIH, USA) will visit Amsterdam for this symposium that will take place in the afternoon of September 2, '24, at the Medical Faculty building of Vrije Universiteit. Please note the advance registration in connection with the catering.

• 14:00-15:00: Dr Brian Glancy – Sustaining power: building energy networks in striated muscle (see abstract below)
• 15:00-15:30: Dr Richie Goulding – Skeletal muscle mitochondria in healthy ageing and type I diabetes
• 15:30-15:45: Short break
• 15:45-16:15: Dr Melissa Hooijmans - Exercise MR to study mitochondrial function and tissue oxygenation in healthy and diseased skeletal muscle
• 16:15-16:45: Prof Coen Ottenheijm – From brain stimulation to myofibrillar force measurements in patients with skeletal muscle myopathies
• 16:45-17:15: Selection of 3 minute presentations from local PhD students
• 17:15: Drinks and snacks

*Dr Brian Glancy: Sustaining Power: Building Energy Networks in Striated Muscle

Abstract: Skeletal muscle is the most abundant tissue in humans and faces near instantaneous changes in demand for force production lasting from seconds to minutes to hours. Initiating and maintaining muscle contraction requires rapid, coordinated movement of signals and material within and among various structures located throughout the relatively large muscle cell. This seminar will focus on how energy is distributed throughout striated muscle cells to sustain muscle contractions, deficits in which have been implicated in many pathologies including diabetes and muscular dystrophy as well as aging. In particular, I will discuss how the structure and function of the cellular energy distribution system are optimized as part of the integrated muscle cell to maintain energy homeostasis during the large change in energy demand caused by the onset of muscle contraction.

For more information or questions, please contact Rob Wust via email: r.wust@vu.nl