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Marc Hilhorst

Medical Specialist, 01 Internal and External Specialisms Physician, ACS - Atherosclerosis & Ischemic Syndromes Affiliatie UvA Medical Specialist, Nephrology

Specialization

vasculitis; lupus nephritis; IgA nephropathy; kidney transplantation; ANCA

Focus of research

After my PhD thesis in 2015 on anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitis I have remained active in the field of vasculitis. During my nephrology specialization I focused on autoimmune mediated kidney diseases and kidney transplantation. At the moment I have active research projects on ANCA glomerulonephritis, lupus nephritis, IgA nephropathy, IgA vasculitis and kidney transplantation. A subfocus is on monocytes and macrophages in the context of these kidney diseases.

Latest publications

Cardiovascular risk in ANCA-associated vasculitis: Monocyte phenotyping reveals distinctive signatures between serological subsets
Vegting, Y., Hanford, K. M., Jongejan, A., Gajadin, G. R., Versloot, M., van der Bom-Baylon, N. D., Dekker, T., Penne, E. L., van der Heijden, J. W., Houben, E., Bemelman, F. J., Neele, A. E., Moerland, P. D., Vogt, L., Kroon, J. & Hilhorst, M. L., Oct 2024, In: Atherosclerosis. 397, p. 118559 118559.
Research output: Contribution to journal › Article › Academic › peer-review
mRNA-1273 vaccinated inflammatory bowel disease patients receiving TNF inhibitors develop broad and robust SARS-CoV-2-specific CD8+ T cell responses
van den Dijssel, J., Duurland, M. C., Konijn, V. A. L., Kummer, L. Y. L., Hagen, R. R., Kuijper, L. H., Wieske, L., van Dam, K. P. J., Stalman, E. W., Steenhuis, M., Geerdes, D. M., Mok, J. Y., Kragten, A. H. M., Menage, C., Koets, L., Veldhuisen, B., Verstegen, N. J. M., van der Schoot, C. E., van Esch, W. J. E., D'Haens, G. R. AM., & 10 othersLöwenberg, M., Volkers, A. G., Rispens, T., Kuijpers, T. W., Eftimov, F., van Gisbergen, K. P. JM., van Ham, S. M., ten Brinke, A., van de Sandt, C. E. & T2B! immunity against SARS-CoV-2 study group, 1 Apr 2024, In: Journal of autoimmunity. 144, 103175.
Research output: Contribution to journal › Article › Academic › peer-review
T cell activation markers CD38 and HLA-DR indicative of non-seroconversion in anti-CD20-treated patients with multiple sclerosis following SARS-CoV-2 mRNA vaccination
T2B! immunity against SARS-CoV-2 study group, Verstegen, N. J. M., Hagen, R. R., Kreher, C., Kuijper, L. H., van den Dijssel, J., Ashhurst, T., Kummer, L. Y. L., Cabeza, V. P., Steenhuis, M., Duurland, M. C., de Jongh, R., van der Schoot, C. E., Konijn, V. A. L., Mul, E., Kedzierska, K., van Dam, K. P. J., Stalman, E. W., Boekel, L., Wolbink, G., & 34 othersTas, S. W., Killestein, J., Rispens, T., Wieske, L., Kuijpers, T. W., Eftimov, F., van Kempen, Z. L. E., van Ham, S. M., ten Brinke, A., van de Sandt, C. E., vd Kooi, A. J., Raaphorst, J., Zwinderman, A. H. K., Löwenberg, M., Volkers, A. G., D'Haens, G. R. A. M., Takkenberg, R. B., Spuls, P. I., Bekkenk, M. W., Musters, A. H., Post, N. F., Bosma, A. L., Hilhorst, M. L., Vegting, Y., Bemelman, F. J., Fernandez, L., Keijzer, S., Keijser, J. B. D., Cristianawati, O., Voskuyl, A. E., Ruiter, A. M., Broens, B., Nejentsev, S. & Mirfazeli, E. S., 2024, (E-pub ahead of print) In: Journal of Neurology, Neurosurgery and Psychiatry. jnnp-2023-332224.
Research output: Contribution to journal › Article › Academic › peer-review
All publications

Marc Hilhorst

Specialization

Focus of research

Cardiovascular risk in ANCA-associated vasculitis: Monocyte phenotyping reveals distinctive signatures between serological subsets

mRNA-1273 vaccinated inflammatory bowel disease patients receiving TNF inhibitors develop broad and robust SARS-CoV-2-specific CD8+ T cell responses

T cell activation markers CD38 and HLA-DR indicative of non-seroconversion in anti-CD20-treated patients with multiple sclerosis following SARS-CoV-2 mRNA vaccination

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