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                                PhD graduation Timeline and information of your PhD graduation at Amsterdam UMC.
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                                Study quantifies impact of rapid first shock after cardiac arrest It is well known that acting quickly in the event of a cardiac arrest is important, but what does a quick initial shock with a defibrillator mean exactly for patients' chances of survival? Researchers from Amsterdam UMC analysed the data of 3723 patients who had a cardiac arrest outside the hospital and concluded that for the first shock, every minute reduces the chance of survival by 6%. The results of this research were published in the journal Circulation.
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                                Phase Two results with CRISPR-Cas9 gene editing support further development as treatment for hereditary angioedema A single treatment with, a CRISPR-Cas9 based gene editing therapy, is enough to replace the daily medication of patients with hereditary angioedema (HAE), a condition characterized by severe, painful and sudden onset of swelling, sometimes resulting in death. Confirming the findings published earlier this year from researchers from Amsterdam UMC, the University of Auckland and Cambridge University Hospitals NHS Foundation Trust. This phase two study is published today in the New England Journal of Medicine and presented at American College of Allergy, Asthma & Immunology's annual congress on the 26th of October.
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                                Predicting epilepsy after rare stroke Researchers from 15 countries, led by Amsterdam UMC, have developed a way to predict which patients are at risk of epilepsy after a cerebral venous sinus thrombosis (CVT). CVT is a type of stroke that typically affects women between the ages of 20 and 50. The prediction model is now available worldwide free of charge and research it is based on is published in JAMA Neurology.
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                                About the Amsterdam UMC Doctoral School The Amsterdam UMC Doctoral School is to support you during your PhD trajectory and strives to be a well-known and appreciated partner for PhD candidates and their supervisors.
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                                Genetic background of pregnant women can influence the result of the Non-Invasive Prenatal Test Non-Invasive Prenatal Tests (NIPTs) are increasingly an integral part of screening during pregnancies across the world. Research from Amsterdam UMC shows that a pregnant woman's genetic background influences the effectiveness of the test. Data from over 140,000 administered tests in the Netherlands shows that a specific genetic variant, carried by about 7% of women in The Netherlands, increases the odds of inconclusive results and impairs the sensitivity of NIPT. These results are published today in Cell Reports.
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                                Mental health issues are a common phenomenon in elite sport Nearly three-quarters of Dutch elite athletes and forty percent of their coaches report sport-related distress. This is one of the findings from a study conducted by Amsterdam UMC together with NOC*NSF, the organisation which represents the Dutch Olympic Committee and the Dutch Sport Federation, published today in BMJ Open Sport & Exercise Medicine.
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                                Creating an environment where everyone can reach their full potential Firmly based on the scientific insights we gained about human health, fueled by our moral ambition to contribute to society through science, Amsterdam UMC wants to take responsibility as the biggest academic medical center in the Netherlands, to contribute to an international movement that takes the interests of future generations into account. In order to facilitate this, Amsterdam UMC appointed this year its first Future Generations Commissioner, Tessa Roseboom, professor of Early Development and Health.
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                                A step forward in the battle against MRSA Staphylococcus aureus, mostly known from its antibiotic-resistant variant Methicillin-resistant Staphylococcus aureus (MRSA), is among the leading causes of both community- and hospital-acquired infections. According to the most recent data, MRSA killed around 120,000 people in 2022 globally and far more are killed by antibiotic-susceptible strains of S. aureus. So far however, all attempts at developing a protective vaccine for S. aureus have been unsuccessful. Research from Amsterdam UMC, in collaboration with UMC Utrecht, Leiden University, and the University of California, San Diego, have discovered an important immune component that offers protection against infection, suggesting a new direction for the future. These results are published today in Cell Reports Medicine.
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                                Digital consultations improve the rate at which patients receive optimal medication Patients with heart failure, a condition affecting more than 60 million worldwide, are four times more likely to receive the optimal combination of medications after 12 weeks of digital consultations. Researchers from five Dutch hospitals, coordinated by Amsterdam UMC, found that the use of digital consults improved care while maintaining patient satisfaction. These results are published today in Nature Medicine and simultaneously presented at the annual conference of the European Society of Cardiology.
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