General
Seminar Dr. Charlotte Scott
VIB-UGent Center for Inflammation Research, BE
Title: Investigating hepatic macrophage heterogeneity in health and disease
Charlotte Scott obtained her Ph.D. at the University of Glasgow, Scotland in the Lab of Allan Mowat where she investigated mucosal dendritic cells. In 2014, she joined the VIB-UGent Center for Inflammation Research, Belgium, working in the Guilliams lab as a postdoc. In 2019 Dr. Scott received an ERC Starting Grant, became associate professor at the Ghent University and in 2020 a Group Leader at VIB.
Her lab is focused on investigating the functional heterogeneity of hepatic macrophages in the context of tissue damage and inflammation. Recently, her team has been addressing this issue using single-cell and spatial proteogenomics approaches, including CITE-seq, Visium, molecular cartography, and MACSima Imaging Cyclic Staining (MICS). Using these technologies in the mouse and human liver, the team has identified conserved, spatially relevant features regulating recruited hepatic macrophage phenotypes in health and disease.
Lab of Myeloid Cell Biology in Tissue Damage and Inflammation | IRC - VIB (ugent.be)