AI&I Research Highlights

AII Expertise Database Find out about our AII researchers in this database. The purpose of our database is that the researchers of AII can find each other based on name, research topic, technology, disease etc.

Completed

ARCAID - Amsterdam Rheumatology Center for AutoImmune Diseases ARCAID allows us to bring together 20 of the most talented young researchers in biomedicine from all over the world with top translational scientists.

Ongoing

Germline biomarkers of melanoma immunotherapy: an international consortium Biomarkers that predict immunotherapy treatment success or risk of toxicity are urgently needed, to increase clinical benefit of metastatic melanoma patients.

Ongoing

IMI ImmuneImage The objective of Immune-Image is to develop a novel non-invasive imaging strategy for assessing immune cell activation and dynamics.

Ongoing

Lyme borreliosis: diagnosis and management Chronic symptoms attributed to Lyme borreliosis can be challenging to diagnose and treat. This state of the art and systematic review in the BMJ by Kullberg and collaborators offers a roadmap for physicians how to provide the best possible and personalised care for their patients.

Ongoing

Pharmacokinetic and pharmacodynamic target attainment of antibiotics in different patient populations The adequacy of currently used dosing regimens of ciprofloxacin and ceftazidime are explored and if required improved.

Ongoing

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability Isolation of 403 monoclonal antibodies from COVID-19 patients revealed convergent gene usage and multiple target epitopes

Ongoing

Resident immune cells in lesion formation in advanced MS MS is characterized by inflammatory attacks of infiltrating leukocytes at onset but evolves into a progressive disease within the central nervous system.

Ongoing

Selective tumor antigen vaccine delivery to human CD169+ antigen presenting cells using ganglioside-liposomes Current immunotherapies only benefit a minority of cancer patients. We need new approaches to boost patients’ anti-tumor immune responses.

Ongoing

Single domain antibody targeting of the CD1d monomorphic antigen-presenting molecule induces potent anti-tumour activity Camelid-derived single domain antibodies (VHH)5 specific for the human MHC class I-like molecule CD1d can modulate the function of CD1d-restricted T cell populations.

Ongoing

Study of a newfound immunometabolite in macrophages The lab of Jan Van den Bossche investigates how metabolism controls macrophages and disease progression.

Ongoing

TREAT NL (TREatment of ATopic eczema, The Netherlands) registry The TREAT NL registry is a national registry of children and adults with moderate-to-severe atopic eczema (AE).

Ongoing

Amsterdam institute for Immunology and Infectious Diseases

AI&I Research Highlights