General
The ADORE program is an innovative approach to the study and treatment of both cancer and neurological diseases. ADORE aims to develop collaborations between researchers from different fields (oncology, neurology, data science, ethics) to increase synergies in terms of expertise, skills, infrastructure and resources. The program will also invest in state-of-the-art facilities and infrastructure to support cutting-edge research and recruit top talent. Research projects will be brought into ADORE through the focus groups.
These focus groups include key opinion leaders in every topic of interest for ADORE. The members have the role to identify themes and directions that the focus group intends to pursue for the future development of the ADORE concept and research. After selection of the best projects and an iterative process of feedbacks, the focus groups leaders present new projects to the Research Council (ORA) for consideration and support. Focus groups monitor ongoing projects to assess their progress and ensure their successful implementation. At the moment there are six focus groups and each of them is led by at least two experts in the field, respectively working in oncology or neuroscience.
Biobanking and Biomarkers
This focus group lead by Michiel Pegtel & Charlotte Teunissen is a dynamic assembly of interdisciplinary experts dedicated to create unique tissue, liquid, and digital (genomic, imaging) biobanks to better understand the connection between oncological and neurodegenerative diseases. The group aims to create a biobanking and data collection structure adhering to FAIR principles that would allow ADORE users easy access to both biospecimens and data. The group houses multiple experts in the field who have a proven track record in bringing biomarkers to the clinic. The group envisions multimodal approaches with cutting-edge technologies including DNA and RNA sequencing, mass spectrometry, and AI to discover biomarker panels and signatures that correlate with clinical parameters and translate these into practical applications for clinical use.
Several leads were initially identified and highlighted as topics of interest including: Optimal use of our unique & complementary patient materials, Optimal coupling clinical data & samples and Innovative DX assay pipeline(s). Since the first two leads have recently been funded by the ADORE board, we welcome new leads and topics at our next meeting which will take place at Friday the 23rd of August 2024, from 13.00-14.30 in ZH 2 E 14 (vergaderzaal de IJssel). Please send Mandy Chin-Sie-Jen an e-mail (m.f.f.chin-sie-jen@amsterdamumc.nl) if you wish sign up for the focus group and join.
Date and Location
Contact
Please send Mandy Chin-Sie-Jen an e-mail (m.f.f.chin-sie-jen@amsterdamumc.nl) if you wish sign up for the focus group and join.