Specialization

Neurotoxicity and brain imaging

Focus of research

Background
A substantial group of patients that has received chemotherapy report cognitive complaints. These problems are corroborated by neuropsychological studies that show impairments in some patients. The exact nature and causes of these impairments, however, need further elucidation. Therefore, it is important to gain more insight in the influence of chemotherapy on the brain with state-of-the-art imaging techniques.

Purpose
To investigate the late effects of chemotherapy on neuropsychological performance, and MRI brain function and structure in patients that received standard-dose chemotherapy for breast cancer or testicular cancer compared to disease specific and healthy controls.