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Improving access to early-stage lung cancer care in Europe There are stark differences between European countries when it comes to both the reimbursement of, and access to, new treatments for patients with early-stage lung cancer. There are also differences in reimbursement times and indications between the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA). Researchers from Amsterdam UMC Cancer Center Amsterdam analysed the landscape, and their results are published today in The Lancet Regional Health Europe as part of a series on the latest developments in the treatment of this lung cancer.
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Loneliness increases the risk of health deterioration in older adults The loneliness often experienced by older people in our society has a negative effect on their physical health, according to researchers from Amsterdam UMC and the University of Glasgow. Emiel Hoogendijk, epidemiologist at Amsterdam Public Health, analysed research results from more than 130 studies and found that loneliness led to an increase in physical frailty, which in turn increases the risk of adverse health outcomes such as depression, falls and cognitive decline. These results are published today in The Lancet Healthy Longevity.
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Ovulation in a third of trans masculine individuals on testosterone One-third of trans masculine individuals taking testosterone have recently ovulated. This means that they can still get pregnant. If they are sexually active, they should be mindful of this and use contraception. This research by Amsterdam UMC, conducted in collaboration with LUMC, was published today in Cell Reports Medicine.
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Amsterdam UMC to use e-health tool to remotely monitor heart patients at home From today, patients and doctors at Amsterdam UMC's Heart Centre can make use of the app HartWacht (HeartGuard, in English) to supplement their care. Through the use of a small measurement instrument, around the size of a cereal bar, and a mobile app, patients can now have their blood pressure and arrythmias monitored at home. This means that patients need to visit their cardiologist less frequently. For doctors, this means they have more precise measurements and can act quicker where necessary. A ''win-win'' in the eyes of Michiel Winter, cardiologist at Amsterdam UMC and leader of this project.
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Using AI to reduce the number of blood cultures in A&E by 30% As soon as a patient arrives at the Emergency Department (ED), it is essential to speedily assess what is wrong with the patient and how they can be helped. In patients with suspected systemic infection at the ED, blood cultures are used frequently to demonstrate whether there is blood stream infection). Amsterdam UMC's acute AI-team's research has shown that performing routine blood cultures in patients with suspected sepsis is not always necessary. With the use of their own algorithm, the team wants to reduce the number of blood cultures in EDs across the world by 30%.
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Artificial intelligence helps predict whether antidepressants will work in patients In patients with major depression disorder it is, thanks to use of artificial intelligence, now possible to predict within a week whether an antidepressant will work. By inputting a brain scan and an individual's clinical information into an AI algorithm, researchers from Amsterdam UMC and Radboudumc could see up to 8 weeks faster whether or not the medication would work. The results of this study are published today in the American Journal of Psychiatry.
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Ultrasound can be used to detect placenta problems in small babies A Doppler ultrasound that measures the blood flow of small unborn babies can reveal whether or not the placenta is working properly. In case of repeated deviations from these Doppler measurements, additional monitoring of the unborn baby is necessary. These deviations indicate a higher risk of oxygen deficiency and other health problems for the baby. This study by Amsterdam UMC in collaboration with UMC Groningen and 17 other Dutch hospitals is published today in the British Journal of Obstetrics & Gynaecology.
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Gene-editing offers hope for people with hereditary disorder A group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher.
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Getting started
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Top doctors supporting top Dutch athletes The medical supervision of top-level athletes requires the know-how of top doctors. Known as High Performance Partners (HPP), eight doctors from Amsterdam UMC work together with TeamNL to support the country's best athletes. Orthopaedic surgeon Gino Kerkhoffs and paediatrician Annemarie van Bellegem are two of these High Performance Partners.
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