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No persistent cough in four out of five with Tuberculosis More than 80% of patients with tuberculosis, the world’s most deadly infection, do not have a persistent cough, despite this being seen as a key symptom of the disease. The infection is predominantly transmitted by coughing, but probably also through simply breathing. Research, led by Amsterdam UMC and the Amsterdam Institute for Global Heath and Development, analysed data on more than 600,000 individuals in Africa and Asia and found that 82.8% of those with tuberculosis had no persistent cough and 62.5% had no cough at all. These results are published today in the Lancet Infectious Diseases.
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Tuberculosis bacteria also present in those who are not diagnosed with TB Mycobacterium tuberculosis (Mtb), the bacteria that causes a tuberculosis infection, is present in exhaled breath of 90% of those presenting with suspected tuberculosis. This includes those who were negative on conventional sputum testing and not diagnosed with TB. This raises the possibility that those who have tested negative may be unknowingly transmitting the infection. Researchers from the University of Cape Town and Amsterdam UMC analysed results from over 100 patients who presented themselves to clinics in South Africa. These findings are published today in PNAS.
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Progesterone protects babies from preterm birth Women with a short cervix around 20 weeks of pregnancy have an increased risk of preterm birth. Preventing preterm birth in pregnant women with a short cervix is a crucial step in protecting the health of the child. Research from Amsterdam UMC now shows that, in pregnant women with a short cervix around 20 weeks, Progesterone (a hormone) is better than a cervical pessary at reducing the risk of severe preterm birth. This study was published today in the BMJ.
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Legal Research Support (LRS): Confidentiality Agreements and Material Transfer Agreements
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Contact Legal Research Support (LRS) Amsterdam UMC Here you'll find where to send your contract requests and the intake form of Legal Research Support (LRS) Amsterdam UMC.
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Improving access to early-stage lung cancer care in Europe There are stark differences between European countries when it comes to both the reimbursement of, and access to, new treatments for patients with early-stage lung cancer. There are also differences in reimbursement times and indications between the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA). Researchers from Amsterdam UMC Cancer Center Amsterdam analysed the landscape, and their results are published today in The Lancet Regional Health Europe as part of a series on the latest developments in the treatment of this lung cancer.
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Loneliness increases the risk of health deterioration in older adults The loneliness often experienced by older people in our society has a negative effect on their physical health, according to researchers from Amsterdam UMC and the University of Glasgow. Emiel Hoogendijk, epidemiologist at Amsterdam Public Health, analysed research results from more than 130 studies and found that loneliness led to an increase in physical frailty, which in turn increases the risk of adverse health outcomes such as depression, falls and cognitive decline. These results are published today in The Lancet Healthy Longevity.
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Ovulation in a third of trans masculine individuals on testosterone One-third of trans masculine individuals taking testosterone have recently ovulated. This means that they can still get pregnant. If they are sexually active, they should be mindful of this and use contraception. This research by Amsterdam UMC, conducted in collaboration with LUMC, was published today in Cell Reports Medicine.
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Amsterdam UMC to use e-health tool to remotely monitor heart patients at home From today, patients and doctors at Amsterdam UMC's Heart Centre can make use of the app HartWacht (HeartGuard, in English) to supplement their care. Through the use of a small measurement instrument, around the size of a cereal bar, and a mobile app, patients can now have their blood pressure and arrythmias monitored at home. This means that patients need to visit their cardiologist less frequently. For doctors, this means they have more precise measurements and can act quicker where necessary. A ''win-win'' in the eyes of Michiel Winter, cardiologist at Amsterdam UMC and leader of this project.
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Using AI to reduce the number of blood cultures in A&E by 30% As soon as a patient arrives at the Emergency Department (ED), it is essential to speedily assess what is wrong with the patient and how they can be helped. In patients with suspected systemic infection at the ED, blood cultures are used frequently to demonstrate whether there is blood stream infection). Amsterdam UMC's acute AI-team's research has shown that performing routine blood cultures in patients with suspected sepsis is not always necessary. With the use of their own algorithm, the team wants to reduce the number of blood cultures in EDs across the world by 30%.
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