Alzheimer’s disease is a type of dementia. Alzheimer Center Amsterdam aims to find ways to discuss, treat and cure Alzheimer’s disease and other types of dementia. Read here about our latest insights and activities.
It is possible to predict cognitive decline in Alzheimer'sAmsterdam UMC's Alzheimer Centre has developed a prediction model that can predict cognitive decline in patients with mild cognitive impairment or mild dementia due to Alzheimer's disease. The next step is developing an app that uses this prediction model, which would represent an important step towards personalised forecasts for patients. The study is published today in the journal Neurology.
Loneliness increases the risk of health deterioration in older adultsThe loneliness often experienced by older people in our society has a negative effect on their physical health, according to researchers from Amsterdam UMC and the University of Glasgow. Emiel Hoogendijk, epidemiologist at Amsterdam Public Health, analysed research results from more than 130 studies and found that loneliness led to an increase in physical frailty, which in turn increases the risk of adverse health outcomes such as depression, falls and cognitive decline. These results are published today in The Lancet Healthy Longevity.
Alzheimer's diagnosis shortly based on biomarkersAt the International Alzheimer's Congress (AAIC) 2023 in Amsterdam, new guidelines for diagnosing Alzheimer's disease developed by clinicians and researchers from around the world were presented. In these criteria, the disease is diagnosed in the clinic through the use of blood biomarkers, just as with other major diseases such as diabetes and cardiovascular disease.
In search of the role of our immune system in Alzheimer's Disease Amsterdam UMC increasingly shines a light on the role of the immune system in Alzheimer's offering a new perspective in the hunt for an effective treatment. Today, Professor Elga de Vries is awarded an ERC Advanced Grant of €2.5m to continue this, with the BRAIN Project.
Alzheimer's double punishment: Women get it more and do more care giving"Women are both disproportionately affected by Alzheimer's Disease while also bearing the bulk of the caregiving burden," concludes Wiesje van der Flier, Scientific Director of the Alzheimer Center Amsterdam at Amsterdam UMC. For van der Flier, more research is necessary. Not only about how the disease develops biologically in males and females, but also how the gender of caregiving determines the care provided.
Improving the Diagnosis of DementiaToday, ten organisations across the Netherlands join forces to improve the diagnosis of dementia, led by Alzheimer Center Amsterdam, Amsterdam UMC.
World's largest exome sequencing Alzheimer's study finds two new genes that raise risk of disease An international study led by Amsterdam UMC, the Netherlands, Pasteur Institute of Lille, France and the University of Rouen Normandy, France, has led to the discovery of two new 'Alzheimer genes', and evidence for a third. A genetic alteration in any one of these genes can lead to a significantly increased risk of Alzheimer's disease. The study is published today in Nature Genetics.
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