Alzheimer’s disease is a type of dementia. Alzheimer Center Amsterdam aims to find ways to discuss, treat and cure Alzheimer’s disease and other types of dementia. Read here about our latest insights and activities.
Alzheimer's diagnosis shortly based on biomarkersAt the International Alzheimer's Congress (AAIC) 2023 in Amsterdam, new guidelines for diagnosing Alzheimer's disease developed by clinicians and researchers from around the world were presented. In these criteria, the disease is diagnosed in the clinic through the use of blood biomarkers, just as with other major diseases such as diabetes and cardiovascular disease.
In search of the role of our immune system in Alzheimer's Disease Amsterdam UMC increasingly shines a light on the role of the immune system in Alzheimer's offering a new perspective in the hunt for an effective treatment. Today, Professor Elga de Vries is awarded an ERC Advanced Grant of €2.5m to continue this, with the BRAIN Project.
Alzheimer's double punishment: Women get it more and do more care giving"Women are both disproportionately affected by Alzheimer's Disease while also bearing the bulk of the caregiving burden," concludes Wiesje van der Flier, Scientific Director of the Alzheimer Center Amsterdam at Amsterdam UMC. For van der Flier, more research is necessary. Not only about how the disease develops biologically in males and females, but also how the gender of caregiving determines the care provided.
Improving the Diagnosis of DementiaToday, ten organisations across the Netherlands join forces to improve the diagnosis of dementia, led by Alzheimer Center Amsterdam, Amsterdam UMC.
World's largest exome sequencing Alzheimer's study finds two new genes that raise risk of disease An international study led by Amsterdam UMC, the Netherlands, Pasteur Institute of Lille, France and the University of Rouen Normandy, France, has led to the discovery of two new 'Alzheimer genes', and evidence for a third. A genetic alteration in any one of these genes can lead to a significantly increased risk of Alzheimer's disease. The study is published today in Nature Genetics.
Healthy people with abnormal PET scans are at high risk of future memory problems Cognitively healthy individuals with abnormal amyloid-β and tau PET scans have a greatly increased risk of developing mild cognitive symptoms or even dementia within three-and-a-half years, according to new research by Amsterdam UMC's Alzheimer Center and Lund University in Sweden.
Studying Alzheimer's disease more directly with laser microscopyA team of scientists from Vrije Universiteit Amsterdam and Amsterdam UMC conducted research using advanced laser-microscopic methods into the composition of so-called 'plaques' in the brains of deceased Alzheimer's patients.
Opening the blood-brain barrier with ultrasoundFor the first time in Europe, researchers are trying to temporarily open the blood-brain barrier in a non-invasively manner. They do this using an innovative technique applying low-focused ultrasound (FUS). This will allow drugs to reach the brain more easily.
Less psychosocial problems in patients with dementia during the second lockdownIn current times, patients with dementia and their loved ones can adapt more easily to the challenges of a lockdown. This is the conclusion of a study into the psychosocial consequences of the pandemic for patients with dementia and their loved ones. The results were recently published in the Journal of Alzheimer's Disease.