Specialization
Glioma, advanced MRI, clinical implementation, gadolinium reduction
Focus of research
I am a Neuroradiologist interested in advanced imaging and neuro-oncological imaging of both adults and children.
My research line comprises studies on several perfusion techniques, relaxometry, diffusion, APT-CEST, synthetic image reconstruction and their application for treatment-determining imaging. As part of the GliMR 2.0 network the standardization and clinical implementation of these techniques are a key endeavor of my activities.
A special research focus is diagnostics without the use of gadolinium-based contrast agent. Our group pursues this in the Hanarth-funded GLIOCARE project at VUMC in adult glioma patients, the CCA-funded BIG-BBB DEBBIE-ASL project and in a co-operation with Charles University Prague for pediatric patients (PediTuMRI).
My Ph.D. students investigate possibilities for gadolinium use reductions on three levels: unchaining human capacities to interpret gliomas without contrast-enhanced images, investing into advanced MRI techniques that do not require gadolinium and artificial intelligence approaches.