General
On Thursday March 7, the Tager seminar series will continue with a new lecture & master class by PD Dr. Sean Froese, Head of Research, Division of Metabolism, University Children’s Hospital, Zurich. Sean Froese is also a Principal Investigator, his group studies inherited metabolic disorders, in particular those that affect folate and vitamin B12 metabolism. Their vision is to understand disease pathomechanisms, identify new therapeutic targets, and meaningfully impact therapies for rare diseases with unmet need.
Program
Start | End | Event | Location (AMC) |
---|---|---|---|
9:30 | 11:30 | Master class | Fonteynzaal |
13:00 | 14:00 | Tager lecture | B0-133 |
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Master class
Before the Tager lecture, we will organize a master class with Dr. Froese. If you are interested in (inherited) metabolic diseases, in folate or vitamine B12, or more generally in career development of a translational researcher, please submit the title and short summary of your project before February 27th through agem@amsterdamumc.nl. We will select 4-5 PhD candidates/postdocs to present their work on March 7, between 9.30-11.30h.
Tager Lecture
Inborn disorders of folate and vitamin B12 metabolism - causes, consequences and the push for novel treatments
Vitamin B12 (cobalamin) and B9 (folate) are essential molecules for human life. However, both compounds require a series of absorption, transport and modification steps to be functional. In this lecture, Dr. Froese will discuss how these vitamins are processed in the human body, how they contribute to essential metabolic pathways, and the impact of their (nutritional or) genetic deficiencies. Using recent examples, he will also discuss the impact of multi-omic technologies in improving diagnosis and treatments for related disorders.
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