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Freeze at your own risk: why -20°C storage messes with renin levels and how to turn it around When blood samples are stored the wrong way, hormone tests can give misleading results. AGEM researchers at the Amsterdam UMC Endocrine Laboratory found that renin, an important marker for diagnosing causes of high blood pressure, can appear falsely elevated if serum samples are stored at -20 °C. Their study also points to a simple fix: using special collection tubes with enzyme inhibitors, which prevent or even reverse the false rise in renin levels.
