Dr. Scheper, trained as an RNA biologist at Utrecht University, started working on the export of misfolded proteins from the endoplasmic reticulum during her time at Cambridge University, UK, and developed a strong research program in Amsterdam that investigates the role of proteostasis in neurodegenerative disorders such as Alzheimer’s disease, frontotemporal dementia and Parkinson’s disease. Since 2013, Dr. Scheper is principal investigator at FGA, and has built a multidisciplinary team and a prominent international reputation in the field, with excellent publications and strong external funding. Dr. Scheper is also a familiar face in national media for outreach activities, laymen talks and fundraisers.
The purpose of the new chair is to initiate and conduct research to gain and deepen understanding of the role of proteostatic stress mechanisms in the pathogenesis of neurodegenerative diseases. This insight will lead to the identification of new targets for therapeutic intervention and associated biomarkers for therapy monitoring. Additionally, the chair focuses on the utilization of the results of this research through valorization towards the industry as well as science communication towards the general public.
Read this article on the CNCR website.