Specialization
T cell metabolism
Focus of research
Investigating whether improving T cell metabolism in CLL can improve efficacy of Chimeric Antigen Receptor therapy.
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Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells
Waanders, L., van der Donk, L. E. H., Ates, L. S., Maaskant, J., van Hamme, J. L., Eldering, E., van Bruggen, J. A. C., Rietveld, J. M., Bitter, W., Geijtenbeek, T. B. H. & Kuijl, C. P., 18 Apr 2023, In: Journal for Immunotherapy of Cancer. 11, 4, p. 1-13 13 p., jitc-2022-005839.Research output: Contribution to journal › Article › Academic › peer-review
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Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment
Chen, Z., Simon-Molas, H., Cretenet, G., Valle-Argos, B., Smith, L. D., Forconi, F., Schomakers, B. V., van Weeghel, M., Bryant, D. J., van Bruggen, J. A. C., Peters, F. S., Rathmell, J. C., van der Windt, G. J. W., Kater, A. P., Packham, G. & Eldering, E., 11 Aug 2022, In: Blood. 140, 6, p. 630-643 14 p.Research output: Contribution to journal › Article › Academic › peer-review
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Depletion of CLL cells by venetoclax treatment reverses oxidative stress and impaired glycolysis in CD4 T cells
van Bruggen, A. A. C., van der Windt, G. J. W., Hoogendoorn, M., Dubois, J., Kater, A. P., Peters, F. S. & van Bruggen, J. A. C., 26 Jul 2022, In: Blood advances. 6, 14, p. 4185-4195 11 p., 14.Research output: Contribution to journal › Article › Academic › peer-review
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