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Unraveling resistance mechanisms to the novel nucleoside analog RX-3117 in lung cancer: insights into DNA repair, cell cycle dysregulation and targeting PKMYT1 for improved therapy
Vahabi, M., Xu, G., Sarkisjan, D., Hassouni, B. E., Mantini, G., Donati, V., Wang, B., Lencioni, G., Honeywell, R. J., Deng, D., Strano, S., Peters, G. J., Blandino, G. & Giovannetti, E., 1 Dec 2025, In: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 44, 1, 217.Research output: Contribution to journal › Article* › Academic › peer-review
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Rx-3117 (Fluorocyclopentenyl-cytosine)-mediated down-regulation of dna methyltransferase 1 leads to protein expression of tumor-suppressor genes and increased functionality of the proton-coupled folate carrier
Sarkisjan, D., Julsing, J. R., El Hassouni, B., Honeywell, R. J., Kathmann, I., Matherly, L. H., Lee, Y. B., Kim, D. J. & Peters, G. J., Apr 2020, In: International journal of molecular sciences. 21, 8, 2717.Research output: Contribution to journal › Article* › Academic › peer-review
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Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
Dirkse, A., Golebiewska, A., Buder, T., Nazarov, P. V., Muller, A., Poovathingal, S., Brons, N. H. C., Leite, S., Sauvageot, N., Sarkisjan, D., Seyfrid, M., Fritah, S., Stieber, D., Michelucci, A., Hertel, F., Herold-Mende, C., Azuaje, F., Skupin, A., Bjerkvig, R. & Deutsch, A. & 2 others, , 1 Dec 2019, In: Nature communications. 10, 1, 1787.Research output: Contribution to journal › Article* › Academic › peer-review
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