Specialization
Cerebral glucose metabolism, perioperative neurocognitive disorders, circadian rhythm
Focus of research
My research interests are centered around three primary pillars: cerebral glucose metabolism, circadian rhythm, and perioperative neurocognitive disorders (PNCD).
In the realm of cerebral glucose metabolism, I investigate alterations in glucose transport and alternative glycolysis pathways post-traumatic brain injury, and the implications of elevated cerebrospinal fluid (CSF) glucose levels and diabetes mellitus on the neurotoxic polyol pathway.
Additionally, my work on circadian rhythms focuses on the effects of surgery and anesthesia on sleep-wake timing (both in children and adults), exploring the physiological and metabolic impacts on postoperative recovery.
My research on perioperative neurocognitive disorders aims to enhance prediction and diagnosis methods for PNCD in older adults undergoing surgery. This includes the prospective comparison of detection methods for perioperative neurocognitive disorders and the exploration of perioperative brain functioning, including the influence of intraoperative hypotension and anesthesia on cognition.