Amsterdam Gastroenterology Endocrinology Metabolism

Jarom Heijmans

Affiliatie UvA Medical Specialist, Amsterdam Gastroenterology Endocrinology Metabolism MD-PhD, CCA - Cancer biology and immunology Medical Specialist, General Internal Medicine

Specialization

internal medicine with subspecialisations acute medicine and hematology.

Focus of research

Intestinal homeostasis. Stem cell biology, tumor genetics, Translational control in the intestine. infections in immunocompromised patients.

Key publications
Latest publications

Amsterdam Gastroenterology Endocrinology Metabolism

Jarom Heijmans

Specialization

Focus of research

Driver mutations of the adenoma-carcinoma sequence govern the intestinal epithelial global translational capacity

ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response

Expression of UPR effector proteins ATF6 and XBP1 reduce colorectal cancer cell proliferation and stemness by activating PERK signaling

ER stress and the unfolded protein response in gastrointestinal stem cells and carcinogenesis

Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis

Hyperimmune Globulin for Severely Immunocompromised Patients Hospitalized With Coronavirus Disease 2019: a randomized, controlled trial