Amsterdam Gastroenterology Endocrinology Metabolism

High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages

Hoepel, W., Chen, H-J., Geyer, C. E., Allahverdiyeva, S., Manz, X. D., de Taeye, S. W., Aman, J., Mes, L., Steenhuis, M., Griffith, G. R., Bonta, P. I., Brouwer, P. J. M., Caniels, T. G., van der Straten, K., Golebski, K., Jonkers, R. E., Larsen, M. D., Linty, F., Nouta, J., van Roomen, C. P. A. A., & 16 othersvan Baarle, F. E. H. P., van Drunen, C. M., Wolbink, G., Vlaar, A. P. J., de Bree, G. J., Sanders, R. W., Willemsen, L., Neele, A. E., van de Beek, D., Rispens, T., Wuhrer, M., Bogaard, H. J., van Gils, M. J., Vidarsson, G., de Winther, M. & den Dunnen, J., 2 Jun 2021, In: Science Translational Medicine. 13, 596, eabf8654.

Research output: Contribution to journal › Article › Academic › peer-review

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

Amsterdam UMC COVID-19 biobank study group & Amsterdam UMC COVID-19, 26 Feb 2021, In: Science. 371, 6532, abc8378.

Research output: Contribution to journal › Article › Academic › peer-review

Active control of mucosal tolerance and inflammation by human IgA and IgG antibodies

Hoepel, W., Golebski, K., van Drunen, C. M. & den Dunnen, J., Aug 2020, In: Journal of allergy and clinical immunology. 146, 2, p. 273-275 3 p.

Research output: Contribution to journal › Editorial › Academic › peer-review

Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19

Amsterdam UMC Covid-19 Biobank & Hollmann, M. W., 1 Nov 2023, In: Life Science Alliance. 6, 11, e202302106.

Research output: Contribution to journal › Article › Academic › peer-review

Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death

Amsterdam University Medical Center COVID-19 Biobank Study Group, Amsterdam UMC Covid-19 Biobank, Harris, V., Hollmann, M., Horn, J., Hovius, J. W., de Jong, M. D., Paulus, F., van der Poll, T., Raasveld, J., de Rotte, M. C. F. J., Schinkel, M., Schultz, M. J., Stijnis, C. S., van der Valk, M., Veelo, D., Zwinderman, A. H., Brouwer, M. C., Vlaar, A. P. J., van de Beek, D., & 3 othersvan der Wel, N. N., den Dunnen, J. & van't Veer, C., Oct 2023, In: Research and practice in thrombosis and haemostasis. 7, 7, 102213.

Research output: Contribution to journal › Article › Academic › peer-review

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees

Fatebenefratelli-Sacco Infectious Diseases Physicians group & UMC COVID-19 S3/HCW study group, 1 Jan 2023, In: eBioMedicine. 87, p. 104408 104408.

Research output: Contribution to journal › Article › Academic › peer-review