Jeroen den Dunnen

DRS.

Associate Professor, AII - Immunology Associate Professor, AII - Infectious Diseases Affiliatie UvA Associate Professor, Amsterdam Gastroenterology Endocrinology Metabolism Associate Professor, Center of Experimental and Molecular Medicine

Specialization

Focus of research

Key publications
Latest publications

High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages
Hoepel, W., Chen, H-J., Geyer, C. E., Allahverdiyeva, S., Manz, X. D., de Taeye, S. W., Aman, J., Mes, L., Steenhuis, M., Griffith, G. R., Bonta, P. I., Brouwer, P. J. M., Caniels, T. G., van der Straten, K., Golebski, K., Jonkers, R. E., Larsen, M. D., Linty, F., Nouta, J., van Roomen, C. P. A. A., & 16 othersvan Baarle, F. E. H. P., van Drunen, C. M., Wolbink, G., Vlaar, A. P. J., de Bree, G. J., Sanders, R. W., Willemsen, L., Neele, A. E., van de Beek, D., Rispens, T., Wuhrer, M., Bogaard, H. J., van Gils, M. J., Vidarsson, G., de Winther, M. & den Dunnen, J., 2 Jun 2021, In: Science Translational Medicine. 13, 596, eabf8654.
Research output: Contribution to journal › Article › Academic › peer-review
Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity
Amsterdam UMC COVID-19 biobank study group & Amsterdam UMC COVID-19, 26 Feb 2021, In: Science. 371, 6532, abc8378.
Research output: Contribution to journal › Article › Academic › peer-review
Active control of mucosal tolerance and inflammation by human IgA and IgG antibodies
Hoepel, W., Golebski, K., van Drunen, C. M. & den Dunnen, J., Aug 2020, In: Journal of allergy and clinical immunology. 146, 2, p. 273-275 3 p.
Research output: Contribution to journal › Editorial › Academic › peer-review
All publications

Jeroen den Dunnen

Specialization

Focus of research

High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

Active control of mucosal tolerance and inflammation by human IgA and IgG antibodies

Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19

Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees

Jeroen den Dunnen

Specialization

Focus of research

High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

Active control of mucosal tolerance and inflammation by human IgA and IgG antibodies

Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19

Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees

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