Jörg Hamann

DR.

AII - Immunology Affiliatie UvA Other Academic Staff, Experimental Immunology

Specialization

Biobanking, Immunology

Focus of research

Structure, regulation, and function of adhesion family GPCRs
Biology and clinical relevance of tissue-resident immune cells
Preservation, storage, and usage of biological samples

Key publications
Latest publications

The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells
Chang, G.-W., Hsiao, C.-C., Peng, Y.-M., Vieira Braga, F. A., Kragten, N. A. M., Remmerswaal, E. B. M., van de Garde, M. D. B., Straussberg, R., König, G. M., Kostenis, E., Knäuper, V., Meyaard, L., van Lier, R. A. W., van Gisbergen, K. P. J. M., Lin, H.-H. & Hamann, J., 2016, In: Cell reports. 15, 8, p. 1757-1770
Research output: Contribution to journal › Article › Academic › peer-review
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors
Hamann, J., Aust, G., Araç, D., Engel, F. B., Formstone, C., Fredriksson, R., Hall, R. A., Harty, B. L., Kirchhoff, C., Knapp, B., Krishnan, A., Liebscher, I., Lin, H.-H., Martinelli, D. C., Monk, K. R., Peeters, M. C., Piao, X., Prömel, S., Schöneberg, T. & Schwartz, T. W. & 9 others, Singer, K., Stacey, M., Ushkaryov, Y. A., Vallon, M., Wolfrum, U., Wright, M. W., Xu, L., Langenhan, T. & Schiöth, H. B., 2015, In: Pharmacological reviews. 67, 2, p. 338-367
Research output: Contribution to journal › Review article › Academic › peer-review
Characteristics of differentiated CD8(+) and CD4 (+) T cells present in the human brain
Smolders, J., Remmerswaal, E. B. M., Schuurman, K. G., Melief, J., van Eden, C. G., van Lier, R. A. W., Huitinga, I. & Hamann, J., 2013, In: Acta Neuropathologica. 126, 4, p. 525-535
Research output: Contribution to journal › Article › Academic › peer-review
All publications

Defective RNA Polymerase III sensing of mitochondrial DNA in pulmonary epithelial cells impairs type I IFN immunity to SARS-CoV-2
COVID-STORM Clinicians, Amsterdam UMC Covid-19 Biobank, NIAID-USUHS COVID Study Group, COVID Human Genetic Effort, Danish COVID-19 clinicians, COVID-19 DNABR Group, French COVID Cohort Study Group, COVIDeF Study Group & CoV-Contact Cohort, 24 Mar 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 12, e2522111123.
Research output: Contribution to journal › Article › Academic › peer-review
Tocilizumab Efficacy Across Inflammatory Subphenotypes in COVID-19-Related Acute Respiratory Distress Syndrome
Filippini, D. F. L., Khyali, J., Janssen, M., Rademaker, E., Cremer, O. L., van der Poll, T., van Amstel, R. B. E., Endeman, H., Bos, L. D. J., Amsterdam UMC COVID-19, U.C.-1., Algera, A. G., Appelman, B., van Baarle, F., van de Beek, D., Beudel, M., Bogaard, H. J., Bos, L. D. J., Botta, M., de Brabander, J. & Bree, G. & 65 others, Brouwer, M. C., de Bruin, S., Bugiani, M., Bulle, E., Chouchane, O., Cloherty, A., Buis, B. T. P., de Rotte, M. C. F. J., Dijkstra, M., Dongelmans, D. A., Dujardin, R. W. G., Elbers, P., Fleuren, L., Geerlings, S., Geijtenbeek, T., Girbes, A., Goorhuis, B., Grobusch, M. P., Hagens, L., Hamann, J., Harris, V., Hemke, R., Hermans, S. M., Heunks, L., Hollmann, M., Horn, J., Hovius, J. W., de Jong, M. D., Koning, R., Lim, E. H. T., van Mourik, N., Nellen, J., Nossent, E. J., Paulus, F., Peters, E., Piña-Fuentes, D. A. I., van der Poll, T., Preckel, B., Raasveld, J., Reijnders, T., Schinkel, M., Schrauwen, F. A. P., Schultz, M. J., Schuurman, A., Schuurmans, J., Sigaloff, K., Slim, M. A., Smeele, P., Smit, M., Stijnis, C. S., Stilma, W., Teunissen, C., Thoral, P., Tsonas, A. M., Tuinman, P. R., van der Valk, M., Veelo, D. P., Vlaar, A. P. J., Volleman, C., de Vries, H., Vught, L. A., van Vugt, M., Wiersinga, W. J., Wouters, D. & Zwinderman, A. H., Mar 2026, In: Critical care explorations. 8, 3, p. e1392
Research output: Contribution to journal › Article › Academic › peer-review
Erratum: Multiple sclerosis severity variant in DYSF-ZNF638 locus associates with neuronal loss and inflammation (iScience (2025) 28(5), (S2589004225006911), (10.1016/j.isci.2025.112430))
Engelenburg, H. J., van den Bosch, A. M. R., Chen, J. Q. A., Hsiao, C.-C., Melief, M.-J., Harroud, A., Huitinga, I., Hamann, J. R. & Smolders, J., 16 Jan 2026, In: iScience. 29, 1, 114529.
Research output: Contribution to journal › Comment/Letter to the editor › Academic
All publications

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About Amsterdam UMC Research

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Doctoral school

Jörg Hamann

Specialization

Focus of research

The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors

Characteristics of differentiated CD8(+) and CD4 (+) T cells present in the human brain

Defective RNA Polymerase III sensing of mitochondrial DNA in pulmonary epithelial cells impairs type I IFN immunity to SARS-CoV-2

Tocilizumab Efficacy Across Inflammatory Subphenotypes in COVID-19-Related Acute Respiratory Distress Syndrome

Erratum: Multiple sclerosis severity variant in DYSF-ZNF638 locus associates with neuronal loss and inflammation (iScience (2025) 28(5), (S2589004225006911), (10.1016/j.isci.2025.112430))

Research Institutes

Researchers

About Amsterdam UMC Research

News

Research Roadmap

Core facilities

Research Support

Doctoral school

Jörg Hamann

Specialization

Focus of research

The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors

Characteristics of differentiated CD8(+) and CD4 (+) T cells present in the human brain

Defective RNA Polymerase III sensing of mitochondrial DNA in pulmonary epithelial cells impairs type I IFN immunity to SARS-CoV-2

Tocilizumab Efficacy Across Inflammatory Subphenotypes in COVID-19-Related Acute Respiratory Distress Syndrome

Erratum: Multiple sclerosis severity variant in DYSF-ZNF638 locus associates with neuronal loss and inflammation (iScience (2025) 28(5), (S2589004225006911), (10.1016/j.isci.2025.112430))

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