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Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein
Sorrentino, V., Fouchier, S. W., Motazacker, M. M., Nelson, J. K., Defesche, J. C., Dallinga-Thie, G. M., Kastelein, J. J. P., Kees Hovingh, G. & Zelcer, N., 2013, In: European Heart journal. 34, 17, p. 1292-1297Research output: Contribution to journal › Article › Academic › peer-review
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The Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOL
Nelson, J. K., Sorrentino, V., Avagliano Trezza, R., Heride, C., Urbe, S., Distel, B. & Zelcer, N., 2016, In: Circulation Research. 118, 3, p. 410-419Research output: Contribution to journal › Article › Academic › peer-review
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Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism
Lu, X., Meima, M. E., Nelson, J. K., Sorrentino, V., Loregger, A., Scheij, S., Dekkers, D. H. W., Mulder, M. T., Demmers, J. A. A., M-Dallinga-Thie, G., Zelcer, N. & Danser, A. H. J., 2016, In: Circulation Research. 118, 2, p. 222-229Research output: Contribution to journal › Article › Academic › peer-review
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SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain
Hendrix, S., Dartigue, V., Hall, H., Bawaria, S., Kingma, J., Bajaj, B., Zelcer, N. & Kober, D. L., 1 Dec 2024, In: Nature communications. 15, 1, 5732.Research output: Contribution to journal › Article › Academic › peer-review
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Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans
Hendrix, S., Kingma, J., Ottenhoff, R., Valiloo, M., Svecla, M., Sachdev, V., Kovac, K., Levels, J. H. M., Jongejan, A., de Boer, J. F., Kuipers, F., Rimbert, A., Norata, G. D., Loregger, A., Zelcer, N. & Zijlstra, L. F., 1 Dec 2023, In: Nature communications. 14, 1, 5181.Research output: Contribution to journal › Article › Academic › peer-review
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Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2
Vacondio, D., Nogueira Pinto, H., Coenen, L., Mulder, I. A., Fontijn, R., van het Hof, B., Fung, W. K., Jongejan, A., Kooij, G., Zelcer, N., Rozemuller, A. J., de Vries, H. E. & de Wit, N. M., 1 Nov 2023, In: Cell Death & Disease. 14, 11, p. 781 781.Research output: Contribution to journal › Article › Academic › peer-review