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The Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOL
Sorrentino, V., Avagliano Trezza, R., Heride, C., Urbe, S., Distel, B. & Zelcer, N., 2016, In: Circulation Research. 118, 3, p. 410-419Research output: Contribution to journal › Article › Academic › peer-review
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Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism
Lu, X., Meima, M. E., Sorrentino, V., Loregger, A., Scheij, S., Dekkers, D. H. W., Mulder, M. T., Demmers, J. A. A., M-Dallinga-Thie, G., Zelcer, N. & Danser, A. H. J., 2016, In: Circulation Research. 118, 2, p. 222-229Research output: Contribution to journal › Article › Academic › peer-review
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The E3 ubiquitin ligase MARCH6 degrades squalene monooxygenase and affects 3-hydroxy-3-methyl-glutaryl coenzyme A reductase and the cholesterol synthesis pathway
Zelcer, N., Sharpe, L. J., Loregger, A., Kristiana, I., Cook, E. C. L., Phan, L., Stevenson, J. & Brown, A. J., 2014, In: Molecular and Cellular Biology. 34, 7, p. 1262-1270Research output: Contribution to journal › Article › Academic › peer-review
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SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain
Dartigue, V., Hall, H., Bawaria, S., Kingma, J., Bajaj, B., Zelcer, N. & Kober, D. L., 1 Dec 2024, In: Nature communications. 15, 1, 5732.Research output: Contribution to journal › Article › Academic › peer-review
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Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans
Kingma, J., Ottenhoff, R., Valiloo, M., Svecla, M., Sachdev, V., Kovac, K., Levels, J. H. M., Norata, G. D., Loregger, A. & Zelcer, N., 1 Dec 2023, In: Nature communications. 14, 1, 5181.Research output: Contribution to journal › Article › Academic › peer-review
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Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2
Vacondio, D., Mulder, I. A., Fontijn, R., Kooij, G., Zelcer, N., Rozemuller, A. J., de Vries, H. E. & de Wit, N. M., 1 Nov 2023, In: Cell Death & Disease. 14, 11, p. 781 781.Research output: Contribution to journal › Article › Academic › peer-review