PI
Specialization

Specialisation

Clinical neuro-oncology | Neuro-oncology research | Spine surgery

 

Focus of research

David Noske is a neurosurgeon and professor of neurosurgery.  He is the founder and  head of the Neuro-oncology Research Group (NRG) at the Amsterdam UMC.

Focus of Research

  • Discriminating pseudo progression vs tumor progression, using Blood Platelets: developing innovative, non-invasive diagnostics through the analysis of tumour-educated blood platelets, to enable detection and discrimination of pseudo vs glioblastoma progression
  • Molecular and Cellular Mechanisms in Cancer: understanding the mechanistic basis of tRNA genes regulation in normal and cancer cells and evaluating whether glioblastoma cells use tRNA expression modulation to support their growth.
  • Convection Enhanced Delivery: This is an innovative approach for local drug delivery in the brain while circumventing the Blood Brain Barrier and avoiding systemic toxicity

 

Activities

  • Neurosurgeon at the Amsterdam UMC
  • Principal investigator at the Amsterdam UMC.
  • Head of the Neuro-oncology Research Group (NRG)
  • Consultant at the NKI-AvL cancer hospital Amsterdam