Amsterdam Cardiovascular Sciences

Breath-taking discoveries: the relationship between COVID-19 and the diaphragm Researchers from the Intensive Care Medicine and Physiology departments were the first in the world to show that diaphragm muscle fibers possess the required receptors for the corona virus and that virus particles invaded the diaphragm muscle fibers.

Trombosis & COVID-19: addressing thrombosis-specific questions in COVID-19 patients Researchers of the Vascular Medicine department were one of the first to publish about the risk of venous thromboembolism (VTE) in COVID-19 patients.

Severe COVID-19: Is complement the way out? International phase III trial targeting the complement system to treat severe COVID-19.

CounterCOVID study: oral imatinib to prevent pulmonary vascular leak in COVID-19 Translational COVID-19 research that has led to clinical application of imatinib with the potential of a global impact.

Marfan Syndrome patient involvement in ACS research With the help of Marfan patients and their families, researchers at the Medical Biochemistry and Clinical Genetics departments are able to study novel ways to treat Marfan syndrome and its symptoms.

Patient involvement in cardiovascular research Two heart patients who are passionately committed to the involvement of patients in cardiovascular research at Amsterdam UMC and beyond.

HEART (Hogeschool van Amsterdam En Amsterdam UMC Research Team): Ten years of interdisciplinary research collaboration The Amsterdam UMC Heart Center has developed a successful research collaboration with the Amsterdam University of Applied Science, Faculty of Health.

Endothelial dynamics in blood vessels Studying the impact of mechanical forces on endothelial interactions with the extracellular surroundings and the contacts between endothelial cells by using advanced microscopy approaches.

Bacteriophages as drivers of gut microbiome composition and function and type 2 diabetes Targeting the gut microbiome serves as a preventive measure for the development of type 2 diabetes or to lower the burden on those already affected.

Developing immunotherapy for atherosclerosis: a challenging adventure Immunotherapy is integrated in oncology treatment, but the exploitation in cardiovascular disease is in its infancy. Lowering inflammation is an important strategy for combating cardiovascular disease.

Biological insights to find novel therapies for treatment-resistant forms of heart failure Researchers of the Experimental Cardiology department work together to unravel the underlying mechanisms of hereditary forms of heart failure.