Before the heart thickens: unraveling the early origins of hypertrophic cardiomyopathyHypertrophic cardiomyopathy (HCM) is the most common genetic heart disease, but why symptoms vary so widely between patients with the same DNA defect has long remained unclear. In her thesis, Floor van den Dolder shows that changes in heart function and energy metabolism occur before the heart muscle thickens. Her findings call for earlier detection in people with a genetic predisposition.
Researching the role of methylglyoxal in diabetic complications in Vancouver with the ACS Work Visit GrantOluwatomisono Akinrimisi, PhD Candidate at Amsterdam UMC, visited the BC Children's Hospital Research Institute and the University of British Columbia in Vancouver with the support of the ACS Work Visit Grant. There, he investigated the role of methylglyoxal in diabetic complications and vascular dysfunction — and laid the foundation for new collaborations between the two institutes.
Researching the genetic basis of hypertrophic cardiomyopathy in London with the ACS Work Visit GrantMarion van Vugt, Postdoctoral Researcher at Amsterdam UMC, visited University College London (UCL) with the support of the ACS Work Visit Grant. There, she investigated the role of rare and intermediate-effect genetic variants in hypertrophic cardiomyopathy — and laid the foundation for new collaborations between the two institutes.
